Abstract Background Temozolomide (TMZ) is the most commonly used chemotherapeutic agent used to treat glioblastoma (GBM), which causes significant DNA damage to highly proliferative cells.Our observations have added to accumulating evidence that TMZ induces stress-responsive cellular programs known to promote cell survival, including autophagy.As s
The cell wall of pathogenic fungi plays import roles in interaction with the host, so that its composition and SUNGLASSES structure may determine the course of infection.Here we present an overview of the current and past knowledge on the cell wall constituents of Paracoccidioides brasiliensis and P.lutzii.These are temperature-dependent dimorphic
A direct conversion modulator-demodulator with BRAZIL ACAI even harmonic mixers with emphasis on noise analysis is presented.The circuits consist of even harmonic mixers (EHMs) realized with antiparallel diode pairs (APDPs).We evaluate the different levels of I/Q imbalances and DC offsets and use signal space concepts to analyze the bit error rate